The effects of early adrenaline administration on favorable neurological　outcome of out-of-hospital cardiac arrest patients.

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  • Ueta Hiroki
    Graduate school of Emergency Medical System, Kokushikan University
  • Tanaka Hideharu
    Graduate school of Emergency Medical System, Kokushikan University
  • Takyu Hiroshi
    Graduate school of Emergency Medical System, Kokushikan University
  • Sagisaka Ryo
    Graduate school of Emergency Medical System, Kokushikan University
  • Tanaka Shota
    Research Institute of Disaster management and Emergency medical system, Kokushikan University
  • Nakagawa Takashi
    Center for Disaster Medical Sciences, Aichi Medical University

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  • 病院外心停止症例における早期アドレナリン投与と脳機能予後についての検討

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<p>The timing of Adrenaline administration varies depending on the medical control (MC) area in Japan, because Emergency-Life-Saving-Technicians (ELSTs) must follow the local MC protocol. The purpose of the study was to compare the time between the ELSTs contact to administer the first adrenaline (Adrenaline Time) and to compare with good neurological outcome (CPC1-2) among the 47 prefectures. A total of 40,970 Adrenaline administrated patients were extracted from the Utstein style data between 2006 and 2012. Following parameters were compared by 47 prefectures, The correlation of Adrenaline Time and CPC1-2. The average of nationwide Adrenaline Time was 15.5 ± 7.3 min. However, 9.5 ± 5.1 min was the shortest and 19.8 ± 7.5 min was the longest among the 47 prefectures. A statistically significant negative correlation was found between Adrenaline Time and CPC1-2 (y＝-0.1592 x + 5.6343 ; R2＝0.1844). In conclusion, each local MC council must analyze their own outcomes from Utstein data. We suggest the local MC council re-design the protocol for being able to give Adrenaline as quick as possible after ELSTs get on the scene.</p>

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