Shrimp White Spot Syndrome - from Pathology to Pathogenomics

  • Liu Kuan Fu
    Institute of Zoology, National Taiwan University Tungkang Marine Laboratory, Taiwan Fisheries Research Institute
  • Liu Wang-Jing
    Institute of Zoology, National Taiwan University
  • Kou Guang-Hsiung
    Institute of Zoology, National Taiwan University
  • Lo Chu-Fang
    Institute of Zoology, National Taiwan University

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抄録

For shrimp with low-level white spot syndrome virus (WSSV, = PRDV) infection, environmental or physiological stresses can trigger replication of the virus and lead to a full-blown outbreak of white spot disease. This review will describe how pathogenomic studies have revealed some of the mechanisms that underlie this aspect of WSSV pathology. In the model that emerges, stressors activate shrimp STAT (signal transducer and activator of transcription), which is then annexed by the virus and used to activate the promoter of the immediate early gene WSSV ie1. This in turn leads to rapid replication of the virus.

収録刊行物

  • 魚病研究

    魚病研究 44 (2), 55-58, 2009

    日本魚病学会

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