Studies on the Enzymatic Production of L-Aspartic Acid from Maleic Acid Part II

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タイトル別名
  • Induction Effect of Malonic Acid

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説明

It was found that malonic acid was replaceable for maleic acid which played an induc-tive role for the formation of the enzyme system concerned with the reaction of L-aspartic acid production from maleic acid.<br> The cells grown in the medium containing malonic acid showed a stronger activity of the above reaction than the cells grown on maleic acid. The induction effect of malonic acid was remarkable when the organism was cultured in an acid medium. Whereas, con-sumption of C14-malonic acid in the medium by the organism was not observed at all in any pH milieu even where the formation of the enzyme system essential for the reaction was fully conducted. It indicated that malonic acid penetrated preferentially in acid milieu into the cells was a non-metabolic inducer like thiomethyl-β-D-galactoside in β-galactosidase system and that permeability barrier might exist in the organism.<br> The formation of cis-trans isomerase which catalyzed the conversion of maleic acid to fumaric acid was much stimulated by the addition of either malonic acid or maleic acid. From these results, it was concluded that L-aspartic acid was produced from maleic acid and ammonium ion by both actions of the inducible cis-trans isomerase and the constitu-tive aspartase.

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詳細情報 詳細情報について

  • CRID
    1390001206467725184
  • NII論文ID
    130003415253
  • DOI
    10.1271/bbb1961.30.345
  • COI
    1:CAS:528:DyaF1cXhtVaitLo%3D
  • ISSN
    18811280
    00021369
  • 本文言語コード
    en
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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