A new antibiotic K-52A, produced by Streptoverticillium roseoverticillatum subsp. albosporum, strain No. K-52.

SHIBATA Motoo, UYEDA Masaru, KIDO Yutaka

doi:10.1080/00021369.1976.10862270

A new antibiotic K-52A, produced by Streptoverticillium roseoverticillatum subsp. albosporum, strain No. K-52.

DOI DOI オープンアクセス

SHIBATA Motoo

Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University
UYEDA Masaru

Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University
KIDO Yutaka

Laboratory of Medicinal Microbiology, Faculty of Pharmaceutical Sciences, Kumamoto University

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説明

Streptoverticillium sp., strain No. K-52, isolated from a soil sample collected in Kumamoto City, was found to produce a new antibiotic, K-52 A. From the results of taxonomic studies, strain No. K-52 was identified as a strain of Streptoverticillium roseoverticillatum subsp. albosporum (Thirumalachar) Locci, Baldacci and Petrolini Baldam 1969.<br> Antibiotic K-52 A produced by this strain was thought to be a saccharide, and inhibited the growth of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa on a chemically defined medium. The growth inhibition was, however, reversed by L-glutamic acid, L-glutamine, L-asparatic acid or L-asparagine.