Biochemical Studies on Naturally Occurring Pteridines

DOI オープンアクセス

書誌事項

タイトル別名
  • Part II. Isolation and Characterization of L-<i>threo</i>-Neopterin, as the <i>Crithidia</i> Factor, and of Isoxanthopterin Produced by <i>Serratia indica</i>

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説明

Two pteridine derivatives (Compound I and II) have been isolated from the synthetic culture fluid on which Serratia indica was grown. Compound I isolated as pale yellow spiny crystals has_??_strong growth-promoting activity for Crithidia fasciculata and was identified as 2-amino-4-hydroxy-6-(L-threo-l', 2', 3'-trihydroxypropyl) pteridine (i. e., L-threo-neopterin) by elemental analysis, by its ultraviolet and infrared absorption spectra, by its fluorescence and excitation spectra, specific rotation, by oxidative degradation study with permanganate and by paper-chromatographic comparison with synthetic L-threo-neopterin. Compound II was identified as 2-amino-4, 7-dihydroxypteridine (i. e., isoxanthopterin) by comparison of its ultraviolet absorption spectra, fluorescence and excitation spectra and by paper-chromatographic behaviours with those of the authentic specimen. The biosynthesis of these pteridines by cell-free extracts of S. indica was also discussed.

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詳細情報 詳細情報について

  • CRID
    1390001206471812480
  • NII論文ID
    130003415497
  • DOI
    10.1271/bbb1961.35.47
  • COI
    1:CAS:528:DyaE3MXhtlGgt78%3D
  • ISSN
    18811280
    00021369
  • 本文言語コード
    en
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
    • OpenAIRE
  • 抄録ライセンスフラグ
    使用不可

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