Stimulation of Insulin Action and Stabilization of Cell Membrane in 3T3-L1 Cells by Glycinin Acidic Subunit A<sub>1a</sub>
書誌事項
- タイトル別名
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- Stimulation of Insulin Action and Stabilization of Cell Membrane in 3T3-L1 Cells by Glycinin Acidic Subunit A1a.
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説明
Glycinin acidic subunit A1a and its trypsinized product (A1a/Try) were found to potentiate insulin-mediated antilipolysis antagonized to isoproterenol in 3T3-L1 preadipocytes and adipocytes. A1a and A1a/Try protected 3T3-L1 preadipocytes from the cytotoxic action of trypan blue. Furthermore, the oxygen consumption in rat liver mitochondria that was accelerated during incubation, which implies an increase in the permeability of the inner membrane, was suppressed by the addition of A1a and A1a/Try. On the other hand, the chymotryptic product of A1a did not show such effects. These results suggest that specific amino acid alignment is required for the functions of A1a and that the insulin-stimulating action of A1a and A1a/Try is closely correlated with their stabilizing effect on cell membranes.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 59 (8), 1485-1488, 1995
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206472770560
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- NII論文ID
- 110002677678
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- NII書誌ID
- AA10824164
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- COI
- 1:CAS:528:DyaK2MXnvFKnu7k%3D
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- ISSN
- 13476947
- 09168451
- http://id.crossref.org/issn/09168451
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- PubMed
- 7549099
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可