Elongation Factor 2 in the Liver and Skeletal Muscle of Mice is Decreased by Starvation.

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  • YOSHIZAWA Fumiaki
    Department of Science of Living, Morioka Junior College, Iwate Prefectural University
  • MIURA Yutaka
    Department of Applied Biological Science, Tokyo Noko University
  • TSURUMARU Kazuki
    Department of Applied Biological Science, Tokyo Noko University
  • KIMATA Yukio
    Research and Education Center for Genetic Information, Nara Institute of Science and Technology
  • YAGASAKI Kazumi
    Department of Applied Biological Science, Tokyo Noko University
  • FUNABIKI Ryuhei
    Department of Applied Biological Science, Tokyo Noko University

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  We examined whether starvation affected the amount of EF-2 protein as well as the level of its mRNA in the liver and skeletal muscle of mice, to understand the molecular mechanism for nutritional adaptation of protein-turnover. Although the amount of EF-2 was diminished by starvation in each of the tissues examined, the amount of EF-2 mRNA did not decrease in parallel with the protein.<br>

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