Kojistatin A, a New Cysteine Protease Inhibitor Produced by<i>Aspergillus oryzae</i>

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  • Kojistatin A, a New Cysteine Protease Inhibitor Produced by Aspergillus oryzae.

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A new cysteine protease inhibitor, named kojistatin A, was found in the extract of a solid culture of Aspergillus oryzae ATCC 20386. The structure of kojistatin A was determined on the basis of chemical and spectroscopic evidence. Kojistatin A specifically inhibited cysteine proteases such as papain, ficin, and bromelain.

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