Identification and Analysis of<i>Ku70</i>and<i>Ku80</i>Homologs in the<i>koji</i>Molds<i>Aspergillus sojae</i>and<i>Aspergillus oryzae</i>
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- TAKAHASHI Tadashi
- Noda Institute for Scientific Research
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- MASUDA Tsutomu
- Noda Institute for Scientific Research
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- KOYAMA Yasuji
- Noda Institute for Scientific Research
書誌事項
- タイトル別名
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- Identification and Analysis of Ku70 and Ku80 Homologs in the koji Molds Aspergillus sojae and Aspergillus oryzae
- Identification and analysis of <italic>Ku70</italic> and <italic>Ku80</italic> homologs in the <italic>koji</italic> molds <italic>Aspergillus sojae</italic> and <italic>Aspergillus oryzae</italic>
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抄録
Ku genes play a key role in the non-homologous end-joining pathway. We have identified Ku70 and Ku80 homologs in the koji molds Aspergillus sojae and Aspergillus oryzae, and have constructed the disruption mutants of Ku70, Ku80, and Ku70–80 to characterize the phenotypic change in these mutants. Neither Ku70- nor Ku80-disrupted strains show hypersensitivity to the DNA damaging agents methylmethane sulfonate (MMS) and phleomycin. Moreover, undesirable phenotypes, such as poor growth or repressed conidiospore formation, were not observed in the Ku-disrupted A. sojae and A. oryzae.
収録刊行物
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- Ｂｉｏｓｃｉｅｎｃｅ， Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， ａｎｄ Ｂｉｏｃｈｅｍｉｓｔｒｙ
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Ｂｉｏｓｃｉｅｎｃｅ， Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， ａｎｄ Ｂｉｏｃｈｅｍｉｓｔｒｙ 70 (1), 135-143, 2006
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206475500928
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- NII論文ID
- 10018535311
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- NII書誌ID
- AA10824164
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- COI
- 1:CAS:528:DC%2BD28XhsVGmtLY%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 7791458
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- PubMed
- 16428831
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可