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Determination of Endogenous Peptides with in Vitro ACE Inhibitory Activity in Normotensive Human Plasma by the Fluorometric HPLC Method.
Bibliographic Information
- Other Title
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- Determination of Endogenous Peptides wi
- Determination of Endogenous Peptides with<i>in Vitro</i>ACE Inhibitory Activity in Normotensive Human Plasma by the Fluorometric HPLC Method
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Description
An in vitro degradation test of angiotensin (ANG) II or III in normotensive supine human plasma from 9 healthy male subjects confirmed the production of smaller ANG metabolites with angio-tensin I-converting enzyme inhibitory activity. These metabolites were identified as ANG (3-8), ANG (4-8), ANG (5-8), and ANG (3-4), whose respective peptide concentrations were determined by our proposed naphthalene-2, 3-dialdehyde (NDA)-HPLC method to be 64±9, 39±5, 176±22, and 197±35 fmol/ml of plasma.
Journal
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 61 (6), 1052-1054, 1997
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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Keywords
Details 詳細情報について
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- CRID
- 1390001206475593216
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- NII Article ID
- 110002678645
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- NII Book ID
- AA10824164
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- COI
- 1:CAS:528:DyaK2sXkt1CisLc%3D
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- ISSN
- 13476947
- 09168451
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- NDL BIB ID
- 4240240
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- PubMed
- 9214772
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed