Screening and Industrial Application of Unique Microbial Reactions Involved in Nucleic Acid and Lipid Metabolisms

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  • OGAWA Jun
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
  • SOONG Chee-Leong
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
  • KISHINO Shigenobu
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
  • LI Qing-Shan
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
  • HORINOUCHI Nobuyuki
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University
  • SHIMIZU Sakayu
    Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University

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Abstract

Bioprocesses, which involve biocatalysts for the production of useful compounds, are expected to become a leading player in green chemistry. The first step in bioprocess development is screening for useful biological reactions in the immense number of microorganisms with infinite diversity and versatility. This review introduces some examples of bioprocess development that started from process design stemming from the discovery of unique metabolic processes, reactions, and enzymes in microbial nucleic acid and lipid metabolisms.

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