Effects of Brewer's Yeast Cell Wall on Constipation and Defecation in Experimentally Constipated Rats.
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- NAKAMURA Tomohiko
- Applied Bioresearch Center, Corporate Research and Development Department, Kirin Brewery Co., Ltd.
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- AGATA Kazue
- Applied Bioresearch Center, Corporate Research and Development Department, Kirin Brewery Co., Ltd.
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- MIZUTANI Mai
- Applied Bioresearch Center, Corporate Research and Development Department, Kirin Brewery Co., Ltd.
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- IINO Hisakazu
- Showa Women’s University
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Brewer’s yeast cell wall (BYC) was tested on constipated male Sprague-Dawley rats that had been induced by loperamide (2 mg/kg of body weight). The preventive effect of BYC on constipation was examined and compared with that of a non-fiber diet (NF) as the control. The dose-response of BYC and the effect on defecation by constipated experimental rats were also compared with the characteristics of cellulose diet (CE) group which served as a control. Defecation was observed to be greater by the rats fed with BYC than by those fed with NF or CE. The fecal water content and level of volatile fatty acids (VFA) in the cecal contents were likewise higher in the rats fed with BYC. These results indicate that the administration of BYC was effective for improving defecation and other parameters related to defecation. These favorable effects of BYC supplemented to the diet are attributed to the fermentation ability, water holding capacity and swelling force in the large intestine.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 65 (4), 774-780, 2001
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206475862784
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- NII論文ID
- 110002680344
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- NII書誌ID
- AA10824164
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- COI
- 1:CAS:528:DC%2BD3MXjsVags7c%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 5768788
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- PubMed
- 11388452
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可