Growth Regulation by Insulin-like Growth Factor-1 in Fish

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  • MORIYAMA Shunsuke
    Laboratory of Molecular Endocrinology, School of Fisheries Sciences, Kitasato University
  • AYSON Felix G.
    Aquaculture Department, Southeast Asian Fisheries Development Center (SEAFDEC AQD)
  • KAWAUCHI Hiroshi
    Laboratory of Molecular Endocrinology, School of Fisheries Sciences, Kitasato University

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  • Growth Regulation by Insulin-like Growth Factor-I in Fish

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  Insulin-like growth factor-I (IGF-I) is a mitogenic polypeptide that plays an essential role in the regulation of development and somatic growth of vertebrates, mainly by mediating growth hormone actions. It has clearly been established that the structure of IGF-I and its biological function has been highly conserved among vertebrates. In this paper, we review the recent developments in the molecular, biochemical, and physiological properties of IGF-I in fish.<br>

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