Effects of Chlorogenic Acid and Its Metabolites on Spontaneous Locomotor Activity in Mice
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- OHNISHI Ryoko
- Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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- ITO Hideyuki
- Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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- IGUCHI Ayumu
- Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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- SHINOMIYA Kazuaki
- Department of Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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- KAMEI Chiaki
- Department of Pharmacology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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- HATANO Tsutomu
- Department of Pharmacognosy, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
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- YOSHIDA Takashi
- Faculty of Pharmaceutical Sciences, Matsuyama University
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Chlorogenic acid possessed a weak caffeine-like psychostimulant property when assessed for its effect on spontaneous locomotor activity in mice. In the evaluation of the effects for the major metabolites of chlorogenic acid which were detected upon incubation with rat feces and/or excreted in urine after oral administration to rats, caffeic and m-coumaric acids were found to be the principal active metabolites, while the others contributed little to this caffeine-like psychostimulant activity.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 70 (10), 2560-2563, 2006
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206477036672
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- NII論文ID
- 10018526235
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 8524569
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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