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Immunomodulatory Effect of (-)-Matairesinol in Vivo and ex Vivo
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- YAMAWAKI Manami
- Faculty of Agriculture, Ehime University
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- NISHI Kosuke
- Faculty of Agriculture, Ehime University
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- NISHIMOTO Sogo
- Center for Marine Environmental Studies, Ehime University
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- YAMAUCHI Satoshi
- Faculty of Agriculture, Ehime University South Ehime Fisheries Research Center, Ehime University
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- AKIYAMA Koichi
- Integrated Center for Sciences, Tarumi Station, Ehime University
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- KISHIDA Taro
- Faculty of Agriculture, Ehime University South Ehime Fisheries Research Center, Ehime University
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- MARUYAMA Masafumi
- Faculty of Agriculture, Ehime University
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- NISHIWAKI Hisashi
- Faculty of Agriculture, Ehime University
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- SUGAHARA Takuya
- Faculty of Agriculture, Ehime University South Ehime Fisheries Research Center, Ehime University
Bibliographic Information
- Other Title
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- Immunomodulatory Effect of (−)-Matairesinol<i>in Vivo</i>and<i>ex Vivo</i>
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Description
Matairesinol is one of the lignan compounds found in a variety of plant foodstuffs. We investigated the immunomodulatory effects of (−)-matairesinol in vivo and ex vivo by using mice. Although we found no significant differences in the IgG, IgA and IgM levels in the serum, the IgE level was strongly suppressed by the uptake of (−)-matairesinol in both intact and ovalbumin-immunized mice. The immunoglobulin produced by lymphocytes from the spleen was not activated by the intake of (−)-matairesinol. However, lymphocytes in such gut-associated lymphatic tissues as Peyer’s patches and mesenteric lymph nodes were activated by the administration of (−)-matairesinol.
Journal
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 75 (5), 859-863, 2011
Japan Society for Bioscience, Biotechnology, and Agrochemistry
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Keywords
Details 詳細情報について
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- CRID
- 1390001206478524416
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- NII Article ID
- 10028272385
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- NII Book ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL BIB ID
- 11088591
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- PubMed
- 21597179
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
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- Abstract License Flag
- Disallowed
