Improved High-Fat Diet-Induced Glucose Intolerance by an Oral Administration of Phytosphingosine

DOI Web Site Web Site PubMed 被引用文献8件 参考文献31件
  • MURAKAMI Itsuo
    Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Advanced Life Sciences, Hokkaido University
  • MITSUTAKE Susumu
    Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Advanced Life Sciences, Hokkaido University
  • KOBAYASHI Naoyuki
    Frontier Laboratories of Value Creation, Sapporo Breweries, Ltd.
  • MATSUDA Junko
    Institute of Glycoscience, Tokai University
  • SUZUKI Akemi
    Institute of Glycoscience, Tokai University
  • SHIGYO Tatsuro
    Frontier Laboratories of Value Creation, Sapporo Breweries, Ltd.
  • IGARASHI Yasuyuki
    Laboratory of Biomembrane and Biofunctional Chemistry, Faculty of Advanced Life Sciences, Hokkaido University

この論文をさがす

抄録

We have previously reported that phytoceramide and phytosphingosine (PHS) stimulated the transcriptional activity of peroxisome proliferator-activated receptor γ (PPARγ) in cells. PPARγ is a therapeutic target for type 2 diabetes. We found in this study that an oral administration of PHS improved diet-induced glucose intolerance in mice. Since PHS is highly expressed in yeast, PHS in fermented foods may improve diabetes.

収録刊行物

被引用文献 (8)*注記

もっと見る

参考文献 (31)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ