The<i>trans</i>DSL Ligase Ribozyme Can Utilize Various Forms of Modules to Clamp Its Substrate and Enzyme Units
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- ISHIKAWA Junya
- Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University
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- ISOMOTO Nana
- Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University
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- FUJITA Yuki
- Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University
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- FURUTA Hiroyuki
- Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University
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- IKAWA Yoshiya
- Department of Chemistry and Biochemistry, Graduate School of Engineering, Kyushu University PRESTO, Precursory Research for Embryonic Science and Technology, Japan Science and Technology Agency (JST)
書誌事項
- タイトル別名
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- The transDSL Ligase Ribozyme Can Utilize Various Forms of Modules to Clamp Its Substrate and Enzyme Units
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TransDSL is an RNA ligase ribozyme whose enzyme unit joins two RNA fragments constituting a substrate. The enzyme unit recognizes the substrate by means of two clamp modules. We constructed active variants by replacing the original clamp module with various types of interactions. Such flexible modularity would be advantageous in the application of this ribozyme in nanobiotechnology.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 74 (4), 872-874, 2010
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206478741504
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- NII論文ID
- 10027554302
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 10656658
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
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- 使用不可