Soy Isoflavone Equol Perpetuates Dextran Sulfate Sodium-Induced Acute Colitis in Mice
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- SAKAI Tohru
- Department of Public Health and Applied Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School
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- FUROKU Sakina
- Department of Public Health and Applied Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School
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- NAKAMOTO Mariko
- Department of Public Health and Applied Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School
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- SHUTO Emi
- Department of Public Health and Applied Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School
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- HOSAKA Toshio
- Department of Public Health and Applied Nutrition, Institute of Health Biosciences, The University of Tokushima Graduate School
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- NISHIOKA Yasuhiko
- Department of Respiratory Medicine and Rheumatology, Institute for Health Biosciences, The University of Tokushima
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- SONE Saburo
- Department of Respiratory Medicine and Rheumatology, Institute for Health Biosciences, The University of Tokushima
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The effects of the soy isoflavones, genistein, daidzein and equol, on experimental colitis were examined. Equol severely perpetrated dextran sulfate sodium (DSS)-induced colitis as evaluated by the weight loss. Production of the anti-inflammatory cytokine, IL-10, from T cells was decreased in the equol-treated mice. The results show that the soy isoflavone, equol, played an important role in the inflammatory response in the gastrointestinal tract.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 75 (3), 593-595, 2011
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390001206480009472
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- NII論文ID
- 10028202155
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 11051927
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可