Rubralactone, Rubralides A, B and C, and Rubramin Produced by<i>Penicillium rubrum</i>

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  • KIMURA Yasuo
    Department of Biological and Environmental Chemistry, Faculty of Agriculture, Tottori University
  • YOSHINARI Takashi
    Department of Biological and Environmental Chemistry, Faculty of Agriculture, Tottori University
  • KOSHINO Hiroyuki
    RIKEN (The Institute of Physical and Chemical Research)
  • FUJIOKA Shozo
    RIKEN (The Institute of Physical and Chemical Research)
  • OKADA Katsuhide
    Faculty of Education, Art and Science, Yamagata University
  • SHIMADA Atsumi
    Department of Food and Nutrition, Faculty of Food and Nutrition Science, Beppu University

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  • Rubralactone, Rubralides A, B and C, and Rubramin Produced by Penicillium rubrum

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Rubralactone (1), rubralides A, B and C (2–4), rubramin (5), and 2-formyl-3,5-dihydroxy-4-methylbenzoic acid (6), were isolated from Penicillium rubrum, and their structures established by spectroscopic methods including 2D NMR. The effects on plant growth of 1–6 were examined using the lettuce seedling bioassay. Compound 1 promoted root growth. Compounds 2, 3 and 5 inhibited the growth of lettuce seedlings, but 4 and 6 did not have any inhibitory effect on their growth.

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