Hypoglycemic effect of 13-membered ring thiocyclitol, a novel α-glucosidase inhibitor from Kothala-himbutu (Salacia reticulata)

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タイトル別名
  • Hypoglycemic Effect of 13-Membered Ring Thiocyclitol, a Novel .ALPHA.-Glucosidase Inhibitor from Kothala-himbutu (Salacia reticulata)
  • Hypoglycemic effect of 13 membered ring thiocyclitol a novel a glucosidase inhibitor from Kothala himbutu Salacia reticulata
  • Hypoglycemic Effect of 13-Membered Ring Thiocyclitol, a Novel α-Glucosidase Inhibitor from Kothala-himbutu (<i>Salacia reticulata</i>)

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説明

A novel 13-membered ring thiocyclitol, isolated from an aqueous extract of Kothala-himbutu (Salacia reticulata), inhibited α-glucosidase in vitro. The inhibitory activity was investigated by maltose- and sucrose-loading on Wistar rats. This study found significant lowering of postprandial glucose levels, and the potency of 13-membered ring thiocyclitol was confirmed in vivo.

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