Two Modes of Autoregulation of the<i>murR</i>Repressor in<i>Escherichia coli</i>

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  • ISHII Daiki
    Department of Frontier Bioscience and Research Center for Micro-Nano Technology, Hosei University
  • ISHIHAMA Akira
    Department of Frontier Bioscience and Research Center for Micro-Nano Technology, Hosei University
  • YAMAMOTO Kaneyoshi
    Department of Frontier Bioscience and Research Center for Micro-Nano Technology, Hosei University

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タイトル別名
  • Two Modes of Autoregulation of the murR Repressor in Escherichia coli
  • Two modes of autoregulation of the <italic>murR</italic> repressor in <italic>Escherichia coli.</italic>

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説明

The murPQ operon of Escherichia coli encoding the enzymes for degradation of MurNAc is derepressed by MurR (YfeT) in the presence of MurNAc-6-phosphate. MurR also represses its own expression. We found that murR is stimulated in rich medium. This activation involves MurR and most of the IIBC components of the phosphotransferase system, suggesting auto-induction of murR by an activated form of MurR.

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