Effects of Flavangenol on Autonomic Nerve Activities and Dietary Body Weight Gain in Rats

DOI Web Site Web Site 4 Citations 51 References
  • TANIDA Mamoru
    Institute for Protein Research, Osaka University ANBAS Corporation Department of Biomedical Sciences, College of Life Sciences, Ritsumeikan University
  • TSURUOKA Nobuo
    Institute for Health Care Science, Suntory Limited
  • SHEN Jiao
    Institute for Protein Research, Osaka University ANBAS Corporation
  • HORII Yuko
    Institute for Protein Research, Osaka University ANBAS Corporation
  • BEPPU Yoshinori
    Institute for Health Care Science, Suntory Limited
  • KISO Yoshinobu
    Institute for Health Care Science, Suntory Limited
  • NAGAI Katsuya
    Institute for Protein Research, Osaka University ANBAS Corporation

Search this article

Abstract

In a previous report, evidence was presented that flavangenol supplementation has an anti-ischemic effects in rats. In the study presented here, we examined the autonomic effects of intraduodenal (ID) injection of flavangenol in urethane-anesthetized rats and found that it increased sympathetic nerve activity innervating brown adipose tissue (BAT-SNA) in a dose-dependent manner, while it suppressed gastric vagal nerve activity (GVNA). In addition, intra-oral (IO) injection of flavangenol elevated brown adipose tissue temperature (BAT-T). Furthermore, flavangenol drinking for 15 d reduced body weight gain in rats fed a high-fat diet. These results thus suggest that flavangenol supplementation exerts its reducing action on body weight through changes in autonomic neurotransmission.

Journal

Citations (4)*help

See more

References(51)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top