書誌事項
- タイトル別名
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- Quantitative Analysis of the Preferential Orientation of Collagen and Elastin Fibers in Blood Vessel with an Imaging Methodology Combined with Birefringence Measurement
- ケッカン チュウマク ニ オケル コラーゲン/エラスチン センイハイコウセイ カイメイ ノ タメ ノ テイリョウテキ カイセキ シュホウ ノ カクリツ
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<p>Blood vessel exhibits a complicated microstructure depending on the anatomical portion, which enables the realization of its proper mechanical function. In particular, tunica media plays crucial roles in mediating the structural and functional properties of blood vessels. However, the microstructural analysis with quantitative methodology has not been established. In this study, the quantitative analysis of collagen fibers and elastin fibers in tunica media was achieved by combination of a selective staining technique using fluorescent dyes and birefringence measurement with polarized microscopy. The present method quantitatively unveiled the microstructural difference between thoracic aorta and caudal artery. Both types of vessels were comprised of collagen fibers and elastin fibers running along the circumferential direction of tunica media. Interestingly, the degree of preferential orientation of these fibers was markedly increased in thoracic aorta, suggesting that the anisotropic microstructure of vessel varies depending on the anatomical site.</p>
収録刊行物
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- 日本金属学会誌
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日本金属学会誌 82 (3), 64-69, 2018
公益社団法人 日本金属学会
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詳細情報 詳細情報について
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- CRID
- 1390001206491291648
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- NII論文ID
- 130006399290
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- NII書誌ID
- AN00187860
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- ISSN
- 18806880
- 24337501
- 00214876
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- NDL書誌ID
- 028885746
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可