Effects of Container Materials on Platelet Preservation

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  • HONDA Kenji
    Department of Research, Central Blood Center, Japanese Red Cross Society
  • ITOH Hideaki
    Department of Research, Central Blood Center, Japanese Red Cross Society
  • HOSHI Ichiro
    Department of Research, Central Blood Center, Japanese Red Cross Society
  • SASAKAWA Shigeru
    Department of Research, Central Blood Center, Japanese Red Cross Society

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Other Title
  • 血小板保存における保存容器材質の効果
  • ケッショウバン ホゾン ニ オケル ホゾン ヨウキ ザイシツ ノ コウカ

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Description

To investigate the effects of container materials on platelet preservation, platelet-rich plasma was preserved on a Petri dish, the surface of which was coated with various polymers, and the decreases of the number of single platelets and their aggregability were examined. The polymers used were silicone, poly (vinyl chloride), sodium polyacrylate (polyanion), and polyionene (polycation). The rate of decrease in the number of single platelets was in the following order: silicone << poly (vinyl chloride) ≈uncoated glass < polycation. The number of single platelets decreased rapidly on the polyanioncoated surface as well as on the polycation-coated surface. The difference among the effects of polymers was not clearly found in the changes of platelet aggregability with time. The morphological characteristics of platelets adhered onto the Petri dishes were observed: the platelets on the silicone showed discoid-shape, on polycation formed multiple pseudopods, and on poly (vinyl chloride) were spread out.

Journal

  • KOBUNSHI RONBUNSHU

    KOBUNSHI RONBUNSHU 36 (4), 203-207, 1979

    The Society of Polymer Science, Japan

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