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A case of aspergillosis of the maxillary sinus: Discussion of the usefulness of serological examinations.

  • NODA Yoshiko
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, The University of Tokushima
  • MOMOTA Yukihiro
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, The University of Tokushima
  • SATOMURA Kazuhito
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, The University of Tokushima
  • KAMATA Nobuyuki
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, The University of Tokushima
  • ISHIMARU Naozumi
    Clinical Laboratory, Tokushima University Dental Hospital
  • NAGAYAMA MASARU
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, The University of Tokushima

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Other Title
  • 上顎洞に発症したアスペルギルス症の1例 血清学的検査の有用性についての考察
  • discussion of the usefulness of serological examinations
  • 血清学的検査の有用性についての考察

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Abstract

Aspergillosis is caused by infection with Aspergilli. It is often difficult to make an exact diagnosis before identification of Aspergilli by microbial examination because aspergillosis is difficult to differentiate from other diseases. We present a case of aspergillosis of the maxillary sinus that could be diagnosed on serological examination for Aspergilli or fungi specific sugar.<BR>A 51-year-old woman visited to our hospital because of swelling in the gingiva of the maxilla. Radical operation of the maxillary sinus was performed for a clinical diagnosis of aspergillosis of the maxillary sinus. Histopathological examination revealed Aspergilli in the extirpated tissue of the maxillary sinus. Serological examinations showed elevated serum levels of galactomannan and β-D-glucan. Galactomannan is a specific marker for Aspergilli, and β-D-glucan is specific for fungi. Both makers fell to normal levels after operation, Suggesting that serological examinations for galactomannan and β-D-glucan are useful in the diagnosis of aspergillosis of the maxillary sinus.

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