書誌事項
- タイトル別名
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- A case of osteonecrosis of the maxilla induced by a bisphosphonate
- ビスフォスフォネート セイザイ ニ ヨル ト カンガエラレタ ジョウガクコツ エシ ノ 1レイ
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説明
Bisphosphonates, nonmetabolized analogues of pyrophosphate, have been widely used to treat patients with hypercalcemia caused by malignancy, bone metastasis, multiple myeloma, and osteoporosis. Recent studies have documented that bisphosphonates can cause osteonecrosis of the jaws. We report a case of bisphosphonateassociated osteonecrosis of the maxilla. A 72-years-old woman was referred to our clinic for further examination of the upper left premolar region. Intraoral examination revealed necrotic alveolar bone in the upper left premolar region, with swelling of the surrounding soft tissue and exposed necrotic bone at the right side of the upper jaw. The patinet had a past medical history of breast cancer with bone metastases to the ribs and received intravenous pamidronate at a dose of 30 mg every 2 weeks. We suspected bisphosphonate-associated osteonecrosis and performed sequestrectomy after antibiotic therapy and local irrigation. Because the number of patients who receive bisphosphonates is increasing in Japan, dentists, especially oral surgeons, should be careful about bisphosphonate-associated osteonecrosis of the jaw bones.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 54 (3), 155-159, 2008
公益社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001206531062784
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- NII論文ID
- 10027088078
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 9438113
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- CiNii Articles
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可
