Folding Elements of Proteins

DOI Web Site Web Site 25 References
  • ARAI Munehito
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology (AIST)
  • IWAKURA Masahiro
    Institute for Biological Resources and Functions, National Institute of Advanced Industrial Science and Technology (AIST)

Bibliographic Information

Other Title
  • タンパク質のフォールディング・エレメント
  • タンパクシツ ノ フォールディング エレメント

Search this article

Abstract

From the viewpoint of the sequence space, the protein folding problem can be regarded as a problem of searching for the determinants of protein foldability. The concept of “folding elements (FEs)” has emerged from the search for the amino acid sequence essential for a protein to be foldable. Here we review the characteristics of the FEs of a small globular protein, dihydrofolate reductase, and the necessary conditions for the protein to be foldable. We also review the relationship between the FEs and the kinetic folding reaction and propose the FE-assembly model of protein folding.<br>

Journal

  • Seibutsu Butsuri

    Seibutsu Butsuri 45 (3), 140-144, 2005

    The Biophysical Society of Japan General Incorporated Association

References(25)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top