A case of hemodialysis-related amyloidosis presenting with multiple nodules in the tongue

  • NAKAJIMA Takaki
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • OGAWA Atsushi
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • MIZUKI Harumi
    First Department of Oral and Maxillofacial Surgery, School of Dentistry, Iwate Medical University
  • SATO Hirotaka
    Department of Oral Pathology, School of Dentistry, Iwate Medical University
  • SATOH Masanobu
    Department of Oral Pathology, School of Dentistry, Iwate Medical University
  • KUDO Keigo
    Dental Clinic of Morioka Municipal Hospital

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Other Title
  • 舌に多発性腫りゅうを呈した長期透析患者のアミロイドーシスの1例

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Description

A case of amyloidosis presenting with multiple nodules in the tongue is reported. A 70-year-old woman with a history of chronic renal insufficiency and receiving long-term hemodialysis complained of tenderness along the margin of her tongue. Clinical examination and palpation demonstrated multiple, firm ash-yellow nodules. Microscopic examination of a biopsy specimen stained with alkaline Congo red revealed orange staining. Under a polarization microscope, green disdiaclast refraction of amyloid proteins was identified. The histopathological diagnosis of the specimen was amyloidosis. The patient has not noticed any symptoms after biopsy and is currently being observed.

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