A case of histiocytic necrotizing lymphadenitis

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  • TAMURA Takayuki
    Department of Oral Surgery, Tottori Red Cross Hospital
  • TANIO Kazuhiko
    Department of Oral Surgery, Tottori Red Cross Hospital
  • KODANI Isamu
    Division of Oral and Maxillofacial Biopathological Surgery, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine
  • RYOKE Kazuo
    Division of Oral and Maxillofacial Biopathological Surgery, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine

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Other Title
  • 組織球性壊死性リンパ節炎の1例
  • ソシキキュウセイ エシセイ リンパセツエン ノ 1レイ

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Abstract

We report a case of histiocytic necrotizing lymphadenitis. A 33-year-old woman presented with a swelling in the submental region. A physical examination revealed swelling about 20 mm in diameter in the submental region. The clinical diagnosis was lymphadenitis of the submental region. Magnetic resonance imaging and ultrasonic examination revealed swollen lymph nodes. Treatment with antibiotics was ineffective. On the basis of clinical findings and blood tdsts, it was difficult to make a diagnosis. Under local anesthesia, a biopsy of the submental lymph nodes was performed. Histopathologic examination showed proliferation of lymphocytes and histiocytes, apoptotic bodies, and a necrotic lesion. A definitive diagnosis of histiocytic necrotizing lymphadenitis was made. There was no sign of recurrence for 1 year 8 months.

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