A case of Churg-Strauss syndrome diagnosed in association with cheek pain

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  • YANAMOTO Souichi
    Department of Clinical Oral Oncology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences
  • KAWANO Toshihiro
    Department of Clinical Oral Oncology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences
  • ROKUTANDA Satoshi
    Department of Clinical Oral Oncology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences
  • MIYAKOSHI Masaaki
    Department of Clinical Oral Oncology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences
  • NARUSE Tomofumi
    Department of Clinical Oral Oncology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences
  • UMEDA Masahiro
    Department of Clinical Oral Oncology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences

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Other Title
  • 頬部疼痛を契機に発見されたChurg-Strauss症候群の1例
  • 頰部疼痛を契機に発見されたChurg-Strauss症候群の1例
  • ホオブ トウツウ オ ケイキ ニ ハッケン サレタ Churg-Strauss ショウコウグン ノ 1レイ

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Abstract

Churg-Strauss syndrome is a rare, systemic inflammatory disease characterized by pre-existing type-I allergic symptoms, such as bronchial asthma or allergic rhinitis, and necrotic and granulomatous vasculitis with eosinophilia. We describe our experience with a case of this disease associated with cheek pain.<br>A 64-year old man was referred to our hospital because of pain of the cheek and fever of unknown. He had a past history of chronic sinusitis. Computed fomography and magnetic resonance imaging showed bilateral multiple cystic lesions in the maxilla, and a postoperative maxillary cyst with infection was diagnosed initially.<br>The patient received antibiotic therapy, but the symptoms did not improve. Blood examinations revealed eosinophilia and an increased serum IgE level. Symptoms of mononeuritis multiplex of the arm and leg, renal disorder, and micro-cerebral hemorrhage developed sequentially, and Churg-Strauss syndrome was given diagnosed. He received prednisolone and high-dose gamma globulin therapy, and the symptoms improved.

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