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- 上田 太郎
- 工業技術院産業技術融合領域研究所バイオニックデザイングループ
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- Patterson R. Bruce
- Molecular and Cellular Biology, University of Arizona
書誌事項
- タイトル別名
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- Swinging lever arm model for force production by myosin: Testing by site-directed mutant approach and analyses of the mechanism by structural genetics.
- ミオシン クビフリセツ ブイ トクイテキ ヘンイ ニヨル ケンショウ カラ コ
この論文をさがす
説明
Myosin is a molecular motor that drives movement of actin filaments. It was recently established that the myosin head undergoes a major shape change during the ATP hydrolysis cycle, leading to the popular hypothesis that the shape change provides motile force. Cellular slime mold is uniquely useful not only as an expression system of site-directed mutant myosins, but also as a genetic system to isolate specific mutant myosin genes and their suppressors out of a population of randomly mutagenized cells. Here we present the power of both sitedirected and random approaches to investigate the significance and mechanism of the conformational changes.
収録刊行物
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- 生物物理
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生物物理 37 (1), 331-335, 1997
一般社団法人 日本生物物理学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390001206531788544
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- NII論文ID
- 110001151898
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- NII書誌ID
- AN00129693
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- ISSN
- 13474219
- 05824052
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- NDL書誌ID
- 4129714
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可