化学療法中に慢性炎症性脱髄性多発ニューロパチーを生じた口底癌の1例

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  • A case of oral floor carcinoma associated with chronic inflammatory demyelinating polyneuropathy during chemotherapy
  • カガク リョウホウ チュウ ニ マンセイ エンショウセイ ダツズイセイ タハツ ニューロパチー オ ショウジタ クチテイガン ノ 1レイ

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We report the case of a 73-year-old man with chronic inflammatory demyelinating polyneuropathy (CIDP) that developed during chemotherapy for oral floor carcinoma. While receiving chemoradiotherapy to treat the primary lesion and neck metastatic tumor, the patient had limb numbness, and muscle weakness gradually worsened. He had been given a diagnosis of CIDP on the basis of clinical evidence, the results of electrophysiological examinations, and a biopsy of the sural nerve. Cases of CIDP associated with carcinomas are sometimes reported, and the relevance of anticancer therapy and underlying disease has been suggested. We also considered that chemotherapy or the status of carcinoma was related to the development of CIDP in our patient.

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