Dental surgery in a patient with common variable immunodeficiency: report of a case

DOI Web Site 6 References
  • OKUYAMA Kohei
    Section of Maxillofacial Surgery, Department of Maxillofacial / Neck Reconstruction, Medical and Dental Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • YAMAGUCHI Satoshi
    Section of Maxillofacial Surgery, Department of Maxillofacial / Neck Reconstruction, Medical and Dental Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • KUROHARA Kazuto
    Section of Maxillofacial Surgery, Department of Maxillofacial / Neck Reconstruction, Medical and Dental Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • KUMAGAI Jyunya
    Section of Maxillofacial Surgery, Department of Maxillofacial / Neck Reconstruction, Medical and Dental Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • NAKAKUKI Koichi
    Section of Maxillofacial Surgery, Department of Maxillofacial / Neck Reconstruction, Medical and Dental Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University
  • HARADA Kiyoshi
    Section of Maxillofacial Surgery, Department of Maxillofacial / Neck Reconstruction, Medical and Dental Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University

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Other Title
  • 分類不能型免疫不全症患者に対して観血的歯科治療を施行した1例
  • ブンルイ フノウガタ メンエキ フゼンショウ カンジャ ニ タイシテ カン ケツテキ シカ チリョウ オ シコウ シタ 1レイ

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Abstract

Common variable immunodeficiency (CVID) is one type of primary immunodeficiency (PID) that is characterized by an impaired ability to produce antibodies, associated with severe and recurrent infections. We report the case of a 31-year-old man who was given a diagnosis of CVID with lack of B cells, decreased neutrophil levels, and disturbed production of T cells. The patient required pulpectomy and third-molar extraction. Although he was receiving prophylactic antibiotic and immunoglobulin replacement therapy at regular intervals to reduce the risk of infection and end-organ damage, we planned to additionally administer an intravenous human immunoglobulin preparation immediately before dental treatment and antibiotics in the perioperative period. Single-visit root canal treatment, immediate filling of the left lower second molar, and extraction of 4 third molars were performed without complications during the perioperative period. There was no severe infection as of 6 months after treatment.

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