書誌事項
- タイトル別名
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- Clinical study of tooth extraction in patients receiving warfarin under optimal anticoagulation conditions
- ワルファリン シテキ チリョウイキ デ ノ バッシ ニ カンスル ケントウ
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The purpose of this study was to clarify whether tooth extraction in accordance with the JCS2004 guidelines has any problems. A total of 213 patients (429 teeth) who were receiving anticoagulant therapy with warfarin and required tooth extraction were examined between 2000 and 2008. The study group comprised 123 men and 90 women. The average age of the patients was 66.8 years, and a total of 429 teeth were extracted. The mean International Normalized Ratio (INR) of the patients and was 1.85 before publication of the JCS2004 guidelines and 2.15 after publication. This difference in the INR was significant (p < 0.01). Before 2004, 37 of 55 patients underwent tooth extraction after stopping warfarin, and 3 had postoperative hemorrhage. After 2004, 144 of 158 patients underwent tooth extraction while continuing warfarin. The mean INR value at the time of extraction was 2.03, significantly higher than the value of 1.48 before 2004. There was no increase in postoperative hemorrhage.Bleeding complications in association with the continuation of warfarin also did not occur. The JCS2004 guidelines recommend maintaining the INR at 1.6 to 3.0, while excluding some patients. Our results suggest that tooth extraction can be done safely in association with the continuation of warfarin therapy if the patient's INR is controlled under optimal anticoagulation conditions.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 56 (7), 416-421, 2010
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001206532883584
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- NII論文ID
- 10027843218
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 10783467
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可