A case of acquired hemophilia A incidentally diagnosed on postoperative bleeding after tooth extraction

  • MOTEGI Katsumi
    Department of Oral Medicine, Institute of Health Biosciences, The University of Tokushima Graduate Faculity of Dentistry
  • MOMOTA Yukihiro
    Department of Oral Medicine, Institute of Health Biosciences, The University of Tokushima Graduate Faculity of Dentistry
  • TAKANO Hideyuki
    Department of Oral Medicine, Institute of Health Biosciences, The University of Tokushima Graduate Faculity of Dentistry
  • KANI Kouichi
    Department of Oral Medicine, Institute of Health Biosciences, The University of Tokushima Graduate Faculity of Dentistry
  • YAMAMURA Yoshiko
    Department of Oral Medicine, Institute of Health Biosciences, The University of Tokushima Graduate Faculity of Dentistry
  • AZUMA Masayuki
    Department of Oral Medicine, Institute of Health Biosciences, The University of Tokushima Graduate Faculity of Dentistry

Bibliographic Information

Other Title
  • 抜歯後の止血困難をきっかけに発見された後天性血友病Aの1例
  • バッシ ゴ ノ シケツ コンナン オ キッカケ ニ ハッケン サレタ コウテンセイ ケツユウビョウ A ノ 1レイ

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Acquired hemophilia A is a rare disease. It is caused by the acquirement of factor VIII inhibitor. We report a case of acquired hemophilia A incidentally diagnosed on bleeding after tooth extraction. A 75-yearold woman referred to our hospital because of bleeding after tooth extraction. Hematological examination revealed a prolonged activated partial thromboplastin time (APTT) and decreased coagulation activity of factor VIII. In addition, a high level of factor VIII inhibitor was detected. Therefore, our patient was given a diagnosis of acquired hemophilia A. The patient was admitted to our hospital and received corticosteroids and bypass hemostasis using recombinant coagulation factor VII. On hospital day 42, APTT and factor VIII activity returned to the normal range. Moreover, factor VIII inhibitor disappeared. The patient was discharged and is being treated at a local general hospital.

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