A case of extranodal NK/T cell lymphoma, nasal type arising in the palate
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- MATSUOKA Yudai
- Department of Oral and Maxillofacial Surgery, Kansai Rosai Hospital, Hyogo, Japan
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- ITO Akira
- Department of Oral and Maxillofacial Surgery, Kansai Rosai Hospital, Hyogo, Japan
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- MIMA Junko
- Department of Oral and Maxillofacial Surgery, Kansai Rosai Hospital, Hyogo, Japan
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- ISHIMOTO Shunsuke
- Department of Oral and Maxillofacial Surgery, Kansai Rosai Hospital, Hyogo, Japan
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- ONISHI Yoshimi
- Department of Oral and Maxillofacial Surgery, Kansai Rosai Hospital, Hyogo, Japan
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- KITAMURA Ryuji
- Department of Oral and Maxillofacial Surgery, Kansai Rosai Hospital, Hyogo, Japan
Bibliographic Information
- Other Title
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- 口蓋粘膜原発の節外性NK/T細胞リンパ腫, 鼻型の1例
- コウガイ ネンマク ゲンパツ ノ フシ ガイセイ NK/Tサイボウ リンパシュ,ビガタ ノ 1レイ
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Abstract
Extranodal NK/T cell lymphoma, nasal type is a rare malignant lymphoma, especially in the oral cavity. It is characterized by a necrotizing ulcer, often strongly associated with Epstein-Barr virus. We describe a case of extranodal NK/T cell lymphoma, nasal type found because of antiphlogistic-resistant swelling in the palate. A 73-year-old man was referred to our hospital because of pain and swelling in the left side of the hard palate. Computed tomography showed no evidence of bone destruction, and the symptoms did not change after antibiotic therapy. Therefore, a biopsy was performed, and immunohistochemical analyses revealed positivity for CD56, TIA-1, EBER on in situ hybridization, CD45RO (UCHL1), and CD3 and negativity for CD79a and CD20 (L26). Four courses of DeVIC (CBDCA, VP-16, IFO, DEX) were administered to the patient. There has been no sign of recurrence after chemotherapy. This case demonstrates that antiphlogistic-resistant swelling with no inflammation in the oral cavity can be a clinical sign of extranodal NK/T cell lymphoma, nasal type.
Journal
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- Japanese Journal of Oral and Maxillofacial Surgery
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Japanese Journal of Oral and Maxillofacial Surgery 59 (9), 612-616, 2013
Japanese Society of Oral and Maxillofacial Surgeons
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Details 詳細情報について
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- CRID
- 1390001206533290240
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- NII Article ID
- 130004707993
- 40019815290
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- NII Book ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL BIB ID
- 024910555
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed