非ホジキンリンパ腫の完全寛解後に口蓋粘表皮癌を発症した異時性重複癌の1例

DOI Web Site Web Site 参考文献21件
  • 杉山 円
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科
  • 森 良之
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科 自治医科大学歯科口腔外科学講座
  • 末永 英之
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科
  • 西條 英人
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科
  • 小笠原 徹
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科
  • 星 和人
    東京大学医学部附属病院顎口腔外科・歯科矯正歯科

書誌事項

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  • A case of mucoepidermoid carcinoma of the palate arising as a multiple primary carcinoma after non-Hodgkin's lymphoma
  • ヒホジキン リンパシュ ノ カンゼンカンカイゴ ニ コウガイネンヒョウヒガン オ ハッショウ シタ イジセイ チョウフクガン ノ 1レイ

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Non-Hodgkin's lymphoma is associated with a potential risk of multiple primary carcinoma. Immune suppression related to this disease or the treatment applied has been suggested to cause multiple primary carcinoma. Therefore, appropriate follow-up and management are essential. We report a case of mucoepidermoid carcinoma of the minor salivary gland of the palate that developed after chemotherapy, total-body irradiation, and allogenic bone marrow transplantation for non-Hodgkin's lymphoma 16 years previously. A-32-year-old woman was referred to our hospital because of a painless mass arising in the right side of the palate, which she had recognized 5 years previously. She had received high-dose chemotherapy, total-body irradiation, and allogenic bone marrow transplantation at 16 years of age for non-Hodgkin's lymphoma. She had remained d isease-free for 16 years. An excisional biopsy was performed with the patient under general anesthesia, and the pathological diagnosis during surgery was low-grade mucoepidermoid carcinoma. The resected region was thus extended. Neither recurrence nor metastasis has occurred as of 22 months after surgery.

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