書誌事項
- タイトル別名
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- A case of acquired hemophilia diagnosed incidentally on postoperative bleeding after tooth extraction
- ショウレイ ホウコク バッシ ゴ シュッケツ オ ケイキ ト シテ シンダン サレタ コウテンセイ ケツユウビョウ ノ 1レイ
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抄録
Acquired hemophilia is a rare disease, diagnosed in individuals without any prior bleeding history. The incidence rate is reported to be 1 to 4 patients per million population. We report a case of acquired hemophilia diagnosed incidentally on postoperative bleeding after tooth extraction. A 71-year-old man was referred to our department because of postoperative bleeding after extraction of the lower anterior teeth. The patient had no previous episodes of bleeding tendency. Initial laboratory evaluation revealed a prolonged activated partial thromboplastin time (APTT) and decreased coagulant activity of factor VIII. Further examination revealed the presence of factor VIII inhibitors at the value of 3 Bethesda units. In our patient, the use of activated factor VII concentrates, effective for severe bleeding tendency in patients with acquired factor VII inhibitors, was unnecessary. He successfully responded to treatment with factor VIII concentrates and corticosteroids to control hemorrhage and inhibit the formation of autoantibodies against factor VIII (factor VIII inhibitors).
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 52 (12), 733-737, 2006
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001206533554688
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- NII論文ID
- 10018858812
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 8624752
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可