Botulinum toxin for the treatment of excessive muscle contraction in the oro-facial region: report of two cases

DOI 13 References
  • KANEKO Ryuji
    Department of Oral and Maxillofacial Surgery, Kamo Hospital
  • FUKUHARA Hirokazu
    Department of Oral and Maxillofacial Surgery, Kamo Hospital
  • NIIMI Naoya
    Department of Oral and Maxillofacial Surgery, Kamo Hospital
  • UEDA Minoru
    Department of Oral and Maxillofacial Surgery, Nagoya University Postgraduate School of Medicine

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Other Title
  • 顎顔面領域の筋緊張こう進症にボツリヌス毒素を用いた２例
  • report of two cases

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Abstract

Two cases of excessive muscle contraction in the oro-facial area that were treated by intramuscular injection of botulinum toxin (BTX) are reported.<BR>Patient 1, a 68-year-old woman with a diagnosis of tongue carcinoma, had idiopathic hemifacial spasms. She received local injections of BTX type A (10 to 20U) into facial muscles 3 times. Consequently, facialspasms improved considerably. Electromyography showed reduced muscle fibrillation on blinking.<BR>Patient 2 was a 44-year-old man who had speech disturbance because of involuntary overactive muscles of the mouth region. He received local injections of BTX type A into the lower facial muscles 3 times for a diagnosis of facial spasm and oromandibular dystonia.The dose of BTX ranged from 10 to 30 U. Oral movement disorder improved. The patient's speech is now very smooth and clear.<BR>These two patinets had no disabling side effects. Botulinum therapy seems to be effective in carefully selected patients with overcontraction of oro-facial muscles.

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