A case of central giant cell granuloma of the ramus of the mandible

  • TOHASHI Kazuhito
    Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Tottori University
  • DOI Rieko
    Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Tottori University
  • SHIBATA Masami
    Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Tottori University
  • NAKABAYASHI Motoki
    Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Tottori University
  • KIDANI Kazunori
    Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Tottori University
  • RYOKE Kazuo
    Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Tottori University

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Other Title
  • 下顎枝に発生した中心性巨細胞肉芽腫の1例
  • ショウレイ ホウコク カガク シ ニ ハッセイ シタ チュウシンセイ キョサイボウ ニクゲシュ ノ 1レイ

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We report a case of central giant cell granuloma arising at the ramus of the mandible. The patient was a 12-year-old boy with a painless buccal swelling. Computed tomography (CT) and magnetic resonance imaging (MRI) showed comparatively clear and limited bone resorption at the ramus of the right side of the mandible. Histopathological examination of a biopsy specimen revealed a granulomatous lesion. The lesion was enucleated completely under general anesthesia. The enucleated specimens pathologically showed multinuclear giant cells in granulomatous tissue with inflammatory cells. Giant cells were not distributed uniformly and were abundant around the foci of hemorrhage. The interstitium was rich with microvascular vessels and osteoid formation was present in some regions. The diagnosis was giant cell granuloma. The postoperative course was uneventful, and no recurrence is evident nearly 26 months after operation.

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