A case of spindle cell sarcoma of the maxilla successfully treated with chemotherapy

  • OSANO Hitoshi
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School
  • MATSUMOTO Koichi
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School
  • NOGUCHI Tadahide
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School
  • KUSAMA Mikio
    Department of Dentistry, Oral and Maxillofacial Surgery, Jichi Medical School
  • SAKURAI Shinji
    Separtment of Pathology, Jichi Medical School

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Other Title
  • 化学療法が奏効した上顎紡錘細胞肉腫の1例
  • ショウレイ ホウコク カガク リョウホウ ガ ソウコウ シタ ジョウガク ボウスイ サイボウ ニクシュ ノ 1レイ

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Abstract

A 76-year-old man presented with swelling of the right side of the maxilla. Spindle cell sarcoma was diagnosed on examination of a biopsy sample of the right maxillary sinus. We started CYVADIC (cyclophosphamide, vincristine, adriamycin, dacarbazin) chemotherapy. A favorable clinical response was obtained with 4 courses of chemotherapy. Partial resection of the maxilla was followed by 6 courses of CYVADIC therapy, because a small residual tumor was suspected. Histopathological examination revealed no residual tumor cells.<BR>Chemotherapeutic intervention appears to have been effective, with no apparent recurrence of lesions at present, 14 years after chemotherapy.

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