口腔領域の血管内乳頭状内皮過形成10例の臨床病理学的検討

  • 堀井 信哉
    新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野
  • 小林 孝憲
    新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野 新潟大学医歯学総合病院歯科病理検査室新潟大学大学院医歯学総合研究科口腔病理学分野
  • 飯田 明彦
    新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野
  • 齊藤 力
    新潟大学大学院医歯学総合研究科組織再建口腔外科学分野
  • 林 孝文
    新潟大学大学院医歯学総合研究科顎顔面放射線学講座
  • 朔 敬
    新潟大学医歯学総合病院歯科病理検査室新潟大学大学院医歯学総合研究科口腔病理学分野
  • 高木 律男
    新潟大学大学院医歯学総合研究科顎顔面口腔外科学分野

書誌事項

タイトル別名
  • Clinicopathological study of intravascular papillary endothelial hyperplasia in the oral cavity: Report of 10 cases with a review of the literature
  • コウクウ リョウイキ ノ ケッカン ナイ ニュウトウジョウ ナイヒ カケイセイ 10レイ ノ リンショウ ビョウリガクテキ ケントウ

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抄録

Intravascular papillary endothelial hyperplasia (IPEH) is a reactive lesion histopathologically characterized by papillary proliferation of endothelial cells in organizing thrombi formed in dilated blood vascular spaces.We studied the clinicopathological features of 10 cases of IPEH treated at the Niigata University Hospital during the last 12 years from 1998 through 2009 and reviewed the literature. The patients were 5 men and 5 women.Their age mean was 51.2 years (range, 21 to 72). The lesions were most frequently located in the lower lip (5 cases), followed by the tongue (2 cases), and the buccal mucosa, gingivobuccal fold, and maxillary sinus (1 each). The lesions were all covered by mulberry-colored mucosae, measuring 8.6 mm in average diameter (range, 3 to 12 mm), while they were rather elastic on palpation and did not always fade on compression. Most ofthe clinical diagnoses were hemangioma (7 cases), while the diagnosis of hemangioma was ruled out in 2 cases arising in the lower lip and tongue by ultrasonography, which revealed high blood flow inside the lesion. All cases were surgically removed in accordance with the procedure for hemangioma, without recurrence. Thus, the application of ultrasonographic examination before surgery was suggested to be useful for the differential diagnosis of IPEH from hemangioma.

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