Molecular Mechanism of Light-driven Ion Pumps

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  • KOUYAMA Tsutomu
    Department of Physics, Graduate School of Science, Nagoya University

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  • 光駆動イオンポンプの作動原理
  • ヒカリ クドウ イオンポンプ ノ サドウ ゲンリ

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Abstract

Crystallographic studies of archaeal light-driven ion pumps, including bacteriorhodopsin (BR) and halorhodopsin (HR), have shown that water molecules entrapped in protein cavities play an active role in the ion-translocation mechanism. On the basis of structural data of the reaction intermediates, we have proposed the hypothesis that BR functions as a proton/water antiporter, while HR functions as a proton/HCl antiporter.<br>

Journal

  • Seibutsu Butsuri

    Seibutsu Butsuri 50 (5), 222-227, 2010

    The Biophysical Society of Japan General Incorporated Association

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