書誌事項
- タイトル別名
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- Quantitative Changes in CREB Isoforms and Variants of the Snail Brain in Long-term Memory
- mRNA ゼッタイ テイリョウホウ ニ ヨッテ アキラカ ニ サレタ チョウキ キオクジ ノ テンシャ チョウセツ インシ CREB ノ ゾウゲン
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抄録
The transcription factor, cAMP response element binding protein (CREB), is involved in formation of long-term memory in the brain of many species. There are at least two different isoforms of CREB: the activator isoform (CREB1) and the repressor isoform (CREB2). By use of quantitative real-time PCR, we succeeded in determining CREB1 and CREB2 mRNA copy numbers in the single neuron that plays a key role in the associative learning of the pond snail Lymnaea stagnalis. Further, we characterized the spliced variants of CREB1 mRNA and analyzed the relation between the learning behavior of snails and the expression pattern of these CREB1 mRNA variants in the brain of the learned snails. We here discuss the function and the quantitative changes in CREB isoforms and variants of the snail brain in long-term memory.<br>
収録刊行物
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- 生物物理
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生物物理 51 (1), 018-021, 2011
一般社団法人 日本生物物理学会
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詳細情報 詳細情報について
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- CRID
- 1390001206535002880
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- NII論文ID
- 10027414732
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- NII書誌ID
- AN00129693
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- ISSN
- 13474219
- 05824052
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- NDL書誌ID
- 10995399
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可