Structural Biology of Sec Translocon

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  • タンパク質膜透過装置の構造生物学
  • タンパクシツマク トウカ ソウチ ノ コウゾウ セイブツガク

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Description

<p>Sec translocon, a protein-conducting channel that is conserved in all organisms, functions in cooperation with several proteins including SecA ATPase, a motor protein for protein translocation. To discuss the mechanism of the protein translocation, detail structural information was needed. The first structural report of Sec protein at high resolution is the crystal structure of SecA ATPase in 2001. In this review, I outline the structural biology of the Sec translocon, especially based on our structural studies over the past 10 years.</p>

Journal

  • Seibutsu Butsuri

    Seibutsu Butsuri 58 (2), 078-082, 2018

    The Biophysical Society of Japan General Incorporated Association

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