壮年期男性の健診結果からみた動脈硬化発生のリスク　飲酒頻度からみた脂質及び糖質代謝異常の比較

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  • Risk for arteriosclerotic diseases among middle-aged males undergoing health examination. Abnormal lipid and glucose metabolism in view of alcohol intake frequencies.
  • ソウネンキ ダンセイ ノ ケンシン ケッカ カラ ミタ ドウミャク コウカ ハ
  • Abnormal Lipid and Glucose Metabolism in View of Alcohol Intake Frequencies
  • 飲酒頻度からみた脂質及び糖質代謝異常の比較

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We examined the laboratory data of middle-aged males who underwent health examinations with an emphasis on the frequency of alcohol intake. The following results were obtained.<br>1) In the group with high alcohol intake frequency, serum total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDL-C) and very low density lipoprotein (VLDL) levels tended to be higher and LDL levels increased more significantly than the group with low alcohol intake frequency. However, serum high density lipoprotein-cholesterol (HDL-C) and chyromicron levels were observed to be no different.<br>2) Mild hyperlipidemias in TC, mild and moderate hyperlipidemias in TG and low HDL-cholesterolemias were observed more frequently in the high frequency group. Low LDL-cholesterolemias were noted more frequently in the low frequency group.<br>3) As for serum apoproteins, apo B levels in the high frequency group increased significantly as compared with the low frequency group, and apo A-I levels also tended to be higher. No intergroup differences were observed in apo A-II levels.<br>4) During the oral glucose loading test, plasma glucose levels indicating a border-line curve tended to be higher in the high frequency group than in the low frequency group.<br>5) In the liver function test, serum γ-GTP and Al-Pase activities tended to be elevated in the high frequency group.<br>6) As for past medical histories, no differences were observed in the incidence of gastrointestinal diseases, diabetes mellitus and liver diseases. But incidences of heart diseases and hypertension were higher in the high frequency group than in the low frequency group.<br>In conclusion, health education on alcohol consumption and daily dietary life is warranted especially for middle-aged males for prevention of atherosclerotic diseases.

収録刊行物

  • 栄養学雑誌

    栄養学雑誌 48 (3), 127-133, 1990

    特定非営利活動法人 日本栄養改善学会

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