Effects of Soybean Milk-Intake on Serum and Liver Cholesterols of Rats.

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  • 豆乳摂取がラット血清及び肝臓のコレステロール値に及ぼす影響
  • トウニュウ セッシュ ガ ラット ケッセイ オヨビ カンゾウ ノ コレステロー

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Freeze-dried soybean milk (20%) and 20% equivalents of soybean milk lipid extract and defatted soybean milk were respectively added to the rat diet during cholesterol loading, and their effect on serum and liver lipid metabolism was examined.<br>No effect on the rat body weight and fecal weight was noted. Liver weight increased with cholesterol loading, but the increase was inhibited by addition of soybean milk. Weight of retroperitoneal fat increased in the soybean milk lipid extract group, but decreased in the soybean milk group. In another group (the switchover group) which showed an increase in serum cholesterol and which was subsequently given soybean milk-supplement diet, the fat decreased markedly.<br>The increase in total serum cholesterol was inhibited by the increased amout of soybean milk, soybean milk lipid extract and defatted soybean milk content, but this inhibition was most notably seen in the soybean milk group when compared with other groups.<br>Serum triglyceride decreased in the soybean milk, defatted soybean milk and switchover groups.<br>Liver cholesterol increased with cholesterol loading and this increase was perhaps not affected by inhibition in the present test.<br>Fecal neutral steroid showed an increase in the groups treated with soybean milk, soybean milk lipid extract and defatted soybean milk.

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