鉄欠乏性貧血ラットの回復期における食事たんぱく質およびペプチドの影響

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タイトル別名
  • Effects of Dietary Protein and Peptide on Recovery from Iron Deficiency Anemia by Rats
  • テツ ケツボウセイ ヒンケツ ラット ノ カイフクキ ニ オケル ショクジ タンパクシツ オヨビ ペプチド ノ エイキョウ

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Iron deficiency anemia has been reported to be the most frequent symptom in young adult women. The aim of this study was to verify in iron-deficient rats the efficacy of dietary protein or peptide and the time-course characteristics of recovery from iron deficiency anemia. Rats made anemic by iron-deficient diets for 3 weeks were given egg white protein (EW), egg white peptide (EWP), soy protein isolated (SPI) and soy protein isolated peptide (SPIP) diets with equivalent amounts of protein (N×6.25) and iron (ferric citrate) for 2 weeks. No recovery of hemoglobin concentration from anemia was evident after 2 weeks of treatment with any of the protein or peptide sources. However, the increase of iron in the plasma and hepatic tissue of rats fed with the EW diet was significantly greater than that of the rats fed with the SPI, EWP and SPIP diets. Moreover, after an intragastric administration to normal rats of the EW or EWP solution with an equivalent amount of ferric citrate, the ratio of Fe2+ ions to total iron in the gastrointestinal tract of the rats fed with EW was higher than that in the rats fed with EWP. These results suggest that egg white protein was useful to the process of recovery from iron deficiency anemia due to the improved absorption and utilization of iron.

収録刊行物

  • 栄養学雑誌

    栄養学雑誌 65 (4), 165-171, 2007

    特定非営利活動法人 日本栄養改善学会

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