書誌事項
- タイトル別名
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- Effects of Spa Therapy Combined with Dietary Supplementation with n-3 Fatty Acids on Bronchial Asthma
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N-3 fatty acids are reportedly effective for asthma. In addition, spa therapy has been reported to be effective for patients with asthma. In the present study, the effects of spa therapy combined with perilla seed oil-rich diet (rich in n-3 fatty acid) were examined on asthma. A total of 14 asthmatic patients had a complex spa therapy and consumed a perilla seed oil-rich diet-rich in α-linolenic acid (α-LNA) for 8 weeks. Generation of leukotriene (LT) C4 by leucocytes, respiratory function were analyzed. The generation of LTC4 by leucocytes decreased significantly for 2, 4 and 8 weeks (P<0.05). Peak expiratory flow (PEF) values increased significantly for 2, 4, 6 and 8 weeks (P<0.05). The values of ventilatory parameters [forced vital capacity (FVC), forced expiratory volume in one second (FEV1), forced expiratory flow after 25% of expired FVC (FEF25), forced expiratory flow after 75% of expired FVC (FEF75), mean expiratory flow during the middle half of the FVC (FEF25-75)] revealed a significant increase after 4 and 8 weeks of the modified diet (P<0.05). The results suggest that spa therapy combined with a perilla seed oil-rich diet are effective in the treatment of asthma in terms of its ability to suppress LTC4 generation by leucocytes, and in inducing an improvement of pulmonary function.
収録刊行物
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- 日本温泉気候物理医学会雑誌
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日本温泉気候物理医学会雑誌 66 (3), 171-179, 2003
一般社団法人 日本温泉気候物理医学会
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詳細情報 詳細情報について
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- CRID
- 1390001206569025280
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- NII論文ID
- 10011060582
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- NII書誌ID
- AN00186245
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- ISSN
- 18843697
- 00290343
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- NDL書誌ID
- 6603569
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可