Finding of MRI ALS compared with <sup>15</sup>O-PET in two cases of moyamoya disease with a delay of cerebral circulation and post-operative hyperperfusion

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  • Itagaki Hiroshi
    Department of Neurosurgery, Yamagata University Faculty of Medicine
  • Kokubo Yasuaki
    Department of Neurosurgery, Yamagata University Faculty of Medicine
  • Saso Kanako
    Department of Neurosurgery, Yamagata University Faculty of Medicine
  • Sato Shinji
    Department of Neurosurgery, Yamagata University Faculty of Medicine
  • Yamada Yuki
    Department of Neurosurgery, Yamagata University Faculty of Medicine
  • Sato Shinya
    Department of Neurosurgery, Yamagata University Faculty of Medicine
  • Sonoda Yukihiko
    Department of Neurosurgery, Yamagata University Faculty of Medicine

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  • 脳循環遅延および術後過灌流におけるMRI ASL(arterial spin labeling)所見─<sup>15</sup>O-PET と比較したモヤモヤ病の2 例─

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Abstract

<p>Since MRI arterial spin labeling (ASL) is a non-invasive imaging technique for the evaluation of cerebral circulation, it is gathering attention in recent years as a screening manner. Although the previous reports suggest a good correlation between ASL and 15O-PET, the findings of ASL in the pathologic situation, such as ischemia, hyperperfusion and so on, are not established yet. In this report, we demonstrated the features of ASL compared with 15O-PET in two cases of moyamoya disease with a delay of cerebral circulation and postoperative hyperperfusion. Case 1 showed a delay of cerebral circulation that affects arterial transit time (ATT) verified by cerebral angiography. Although the finding of ASL indicates overestimation by short post-labeling delay (PLD) (1500 msec) due to prolonged ATT, there is a good correlation between ASL with long PLD (2500 msec) and cerebral blood flow (CBF) by 15O-PET. On the other hand, there is a good correlation between ASL with short PLD (1500 msec) and CBF by 15O-PET in Case 2 with postoperative hyperperfusion. Therefore, ASL is non-invasive and simple imaging technique, however, we need to judge the imaging from ASL based on the consideration of ATT.</p>

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